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GeneCanvas :  database of cardiovascular candidate genes and their polymorphisms managed at INSERM/UPMC UMRS 937 (Paris, France) since 1995 (online since 1998). Use the menu above or on the left to navigate in :

  • Articles/supplements : supplements to published articles
  • Articles/short reports : results published online but not in journals
  • Articles/debates and Opinions : discuss hot topics
  • Links : external links to access interesting web sites
  • Downloads : to download software developed in this lab
  • Genes : all gene investigated with links to their polymorphisms and related experimental and statistical information
  • Studies : list of studies of interest to investigate the genetics of cardiovascular disorders
  • Polymorphisms : the complete list of polymorphisms
  • Miscellaneous : sequence data
GRIDHAPLO: A grid package for Genome Wide Haplotype Association Study (GWHAS).
TechnologyGridHaplo implements a sliding windows haplotype analysis approach for
analyzing GWAS SNP data set as described in Tregouet et al. GridHaplo is still under development but its beta version is available for download.
viviane on February 16 2009 11:39:41
0 Comments · 4212 Reads · Print
A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies
StatisticsTHESIAS is a popular software for carrying haplotype association analysis in unrelated individuals. In addition to the command line interface, a graphical JAVA interface is now proposed allowing one to run THESIAS in an user-friendly manner. Besides, new functionalities have been added to THESIAS including the possibility to analyse polychotomous phenotype and X-linked polymorphisms.
viviane on February 09 2007 14:36:26
0 Comments · 7808 Reads · Print
Debates and Opinions
GeneCanvas"Debates and Opinions" to discuss the future of genomics and complex diseases, available texts :

Phenomics and system biology

On Mendelian Randomization

Mega-Studies or better phenotypes ?

Biological system genetics
cervino on October 03 2003 11:25:43
Read More · 8888 Reads · Print
DICE in Genetic Association Studies of Complex Traits
StatisticsApproaching complex diseases by studying one or a few genetic polymorphisms has shown its limitations. It is now increasingly recognized that understanding the genetic basis of complex phenotypes requires not only to investigate all polymorphisms located in functional regions of candidate genes but also to integrate information about the network of genes involved in biological systems of major physiological importance, such as lipid metabolism, cellular adhesion, inflammation...
cervino on September 11 2003 13:10:49
Read More · 12605 Reads · Print
Sequence analysis tools
BioinformaticsSpecial issue of "Nucleic Acids Research" on sequence analysis tools, interesting ... :-) Here
cervino on September 01 2003 07:18:09 · Print
Most Recent Articles
Subject Category Author Views Date
The EURAGEDIC Study Article supplements viviane 1595 14-08-2008 14:53
Diabetes 2008 - A G/T substitution in intron-1 of UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes.
Inflammation gene polymorphisms - online_table_alleles Article supplements viviane 2155 05-12-2006 10:52
J Mol Med 2007; 85:1271-1280. Polymorphisms in 33 inflammatory genes and risk of myocardial infarction - a system genetic approach.
Inflammatory gene polymorphisms - online_table_haplotypes Article supplements viviane 2293 03-07-2006 16:30
J Mol Med 2007; 85:1271-1280. Polymorphisms in 33 inflammatory genes and risk of myocardial infarction - a system genetic approach.
About mega-studies, genetics and cardiovascular diseases Debates and opinions cervino 2537 29-05-2006 19:40
System Genetics 2 - polymorphisms in genes affecting lipid metabolism and inflammation Debates and opinions cervino 3579 14-10-2005 18:02
System Genetics 3 - Atherosclerosis – From Genetic Polymorphisms to System Debates and opinions cervino 3803 14-10-2005 18:07

System Genetics 1 - coronary heart disease genetics Debates and opinions cervino 3009 25-09-2005 16:40
Genome Res 2003;13:1952-60 - Automated detection of informative combined effects in genetic association studies of complex traits Article supplements cervino 2771 08-09-2003 19:56
Eur J Hum Genet. 2004;12:971-4. Cox proportional hazards survival regression in haplotype-based analysis using the stochastic-EM algorithm. Article supplements cervino 3986 10-05-2004 18:10
_Cox2 Article supplements cervino 2663 04-05-2004 18:25
_Cox1 Article supplements cervino 2877 04-05-2004 18:25
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